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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d3c6489ef5f5bcb53de6a85e8a2bb1ce91834319fbb6685ed51585e5e57d6ba' 
  AND token = '/FmBbrkx4uaVcyxel1r9Z8e9lOmS0mhQXmyqWLLIrc4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}