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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e496d11d3e3d81f2a3b6b2ce4abe114298fbc4bac4f29d28140c72ebb9c4ec1' 
  AND token = 'v8N2efPSye4hGx+pb14KeBLjwS/yXNsySpbQTFNUsUQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}