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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2261db0604a875e6c82c86590244a4f24674028aede09260cae422420b222193' 
  AND token = '7uhATK5M8Cmy5HNTip8NQ2ImpHz2QHtVoDl05r+uHGk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}