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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '288672f3b836f7c4453982492504ecd116f1a66b421c59f9470c23da5e670c19' 
  AND token = 'M2EzLqnCaauC8uyFhZpsjhipwiCOt65X4D4M1t4rAdg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}