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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61d03db35fd75f79f35d850a70116d1ed160e69665f23524f0b548877fb03960' 
  AND token = 'xAolL1I0ri/nbeN0BIo/CiZOjxgi03wAjXxm+koIZlQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}