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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52a2312a482d69f305274cd130d7c8a64ed82615003529faced2ee99e85c05d3' 
  AND token = 'OEQ16OrnbqIpwBL7NnboTkhruCcnFn7ANjPc8uREf9M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}