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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '253695622b4d4e6f02415869f3a2fdbd00aeec6558ecf3bc5af8a80c1aacbe2c' 
  AND token = '7gq9UQ0HiTHgcLMwT5msTrflxnqR1crs6kzxDsWjpoY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}