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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c89326670c1853442def094f6415528d4fca3875e4d99010b0bf2e68ac04224' 
  AND token = 'aqIifr9/T1pRqeTVo7bVt2t2Q9ySErz2uWgLc3iHkgE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}