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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '404fb40b1e53b859d36ac571083bf5374725b140d5de62dd2b90b35a302bb1b3' 
  AND token = 'fl9xcRYsOVozNW2WYowCUMyWIlrWCGdRnxT1TykuXOc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}