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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '335cc5ff9fd932b39df58261e2e2b17879036d00592108b70421cac52e099a5e' 
  AND token = 'EVYjaRW7Pks4FPK+mM0RWF2ix/aVYRMAAfARMeN/zN0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}