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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5e6371a1291a3a2604676080837d178105f1a9f1ad6ae697846819b6ca8cefc' 
  AND token = 'rBjxb9Dje3US1g68QwBU8M/IwBIWoRtBWEtPFo6Uc6s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}