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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b776f6fbf838c7a6dbb2113e820131f77515c043413c9e4ff663141398a3850' 
  AND token = 'Ml/R3FWRGP5ZAMPVWuVudTme1Hs1D1Tv8z+kCannkpk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}