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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48c076e943f57a792d66960b51867e8ea16a1289ed9c7177f8de3a21943fbe86' 
  AND token = 'Bh2KMKypY/0deWQPbE2y5CTdWYScTgY0c2wsFAM3xuQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}