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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7bf74348dc2b020781e7bf51b1b19a3d226323c0d508744afe0cb95e90df6d61' 
  AND token = 'Pl0vrfH2g+4R8H2DX9hZKrPF4cuVpF4HlkWqTOoI6pg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}