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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d09de00c584063986e63e5be8b189b57e7f4f460794a242e58a9497fcffe524' 
  AND token = 'TtNF8ne4OhA3tv8W5PvRVQFmX/0av2sSpFqyM4CiUsU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}