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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21c965b135a5e1966efdf144a801c3f6ccd58d3eaed922e5c49087b93d1c5ce2' 
  AND token = 'GQlc0M/yM5twqrrB4VMh9c8Ai6PwqBGjjHhP+i7mNvQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00064

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}