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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a37b8366390110a95651ad1f1c1ba324777237cb99c324dffa352de6304b8ab' 
  AND token = 'npeYqIw+cz3YZxjlW3rAlTNGaJA/EYbJ2jD36vTT0Yc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}