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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '809e7638fc60a2bb9d2dc520200d9a0ca8081efe2bd708df8526555f5ac19920' 
  AND token = 'fSHh+dYL0x4HRjcPIRn3PBqAEwCxabA+QsSs28BKQLk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}