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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b4a02799e55f9b34d67abb1f0bda8b7500e7e7a1e37f21d466099620f187768' 
  AND token = 'r+mZapRLXSiosdWuDln3dJi5Nd8VbVrcQ0mKPhTvzzQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}