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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20690ec2d9fed70e2460802b94ab4449c494dc996468f4a8ff2c5ce14e64cd59' 
  AND token = '+WF5gurHvv53bQifyH0HQ0hwMX0RCRCgmK07xnBZccY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}