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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46620058bb72943f4be3f38b993a6a303d919b18282370d40f3e15547002f1ae' 
  AND token = 'uOQ8ku9/Z2SZGx4hokSb8n+c5idlrBNLYU3smrgHPxI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00127

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}