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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc386dfa8306de3278a7d9e18a5b0f5d4af507e5f3def0ef567bc877703b16a5' 
  AND token = 'Jg2mKrKrVyDXv38h1I47NYVVGUge28/QfXsD1p/snwQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}