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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4eb8b9c733812864c0c23a58863439c5f790fdf849e57f8d0d0717cb2dd46a0' 
  AND token = 'LmOQS8P2bq4RBNLPCl1y0xt6Ha5TRKYwAFe95CzAadQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}