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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11e2358955107844e4a898b5a611fe6569cc74844d0a29f6e47e08e0e042bd2f' 
  AND token = 'lj3QSSL7OtQsErUzrJI9/Ocd2VI+v8zwd/Y/mB3Is0k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}