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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5739b5a93aa64b82e7a23d959e375bdd4ae39016cf8b289a66498eadb049da2a' 
  AND token = 'Yr7cnk5VEow9+l9x6CgRcbmoiXHW1dGrSFGo+LmGObk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}