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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7ea08ec38e410afa12021cfced6cc9dbd78b3c4d53db40eee97df6b70726677' 
  AND token = 'MB+4wFvPGEqZnuYhpSWyc9G9teMMPCFQtyAHpKLKq70=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}