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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5868874c67a13b5b7ecf88742503ca8726f0e5adb9d2aabd4db756bba00d465c' 
  AND token = 'gE1/is0bvmv1aVloGCnf6sOn/VPW4mR+Bmkh0BQFdXM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}