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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5eea6229cbfe4a8e7ad9495936a4bf5e6aee095866e467838a3d07a7088878c8' 
  AND token = 'gTxiibZRXUK3DHgVH8Yaof1+wBFC7S2Gp3Ys3Abv+6Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}