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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1b4c02149e436af27fb43efd4c672a1e22c517ccc037056b8a2c00450c47690' 
  AND token = 'G4xLbVBn1HNahH4PmLD1La/poBvOJzz+bzXTB5rASpA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}