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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a06036349e2d9a40aa624bf54458d2ff278786062b27d9f4c5013fc50200bfa8' 
  AND token = '78W+VJx+wEihMECIN3xwymvCrXMqut0eF23f00Y+bFw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}