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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe19e1899ba1dee9e54442d684610d4019ab490c305641cb52f2e6223a29c265' 
  AND token = 'wCXMtQ0dMvy2400QrB5zisccOrhPSbDSPqOSirQdhms=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}