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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e65c66bd3315ec0cff431bbc60f214fd5fd8368e0bbe8ae3236ac49127b0a9d4' 
  AND token = '5cg9bLBkgxpeJkPDcPYv7OIZYAbeuRxNb+Z5h3i8du4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}