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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '734ead0641f957b8cadc31b923ea9cd2c8a6e64e19bf2db4a892a8ffbf3b5529' 
  AND token = 'D1T9HDtHxU3t3t3gkUXGovLDwJ4aCVVjLLkRzR71yA8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}