SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e495a06459c06d25750cfaf2a16fd6ca4025bf5e0b8776caffa4f3cde2b07cf' 
  AND token = '+AjOv0yfg/tRtCT5q87o17VyxFva9Qehjt9xZVyIhjU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}