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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64413e1511ada5e63fbe23408ba3fde8522f3328e8f903eac1eb596dc5008000' 
  AND token = 'ZyU2T3NJYfWp73+j//SY+FoV8rAjW50jGWoNoDBkcVc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}