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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0efd447f0eb25f0965817dfa8810878aeaf21084fe9fb8637ad5d0b9e34114c1' 
  AND token = '54W1V1Y53UetBSDZ1wNAz88VSP7bJDyF9CDUNE5c6Ro=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}