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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '621b4a77fa7868a65b9487ebd81b40886e2b13c66cd780bfcf61ed45d8d12ca4' 
  AND token = 'Vf8aA01zlNma+vf4u4uSPG6nBDYi82M53hTKWKegsts=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}