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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '400087844b606f536258a808a8401edff93be9d058c49d61c3389e4e86429e98' 
  AND token = '+E3E/MnQmjQJLMeJhHsG/GhlDQm2GWvurgn4bB9pG7g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}