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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d739b046c432380da024274a0cc9fee16752554ed5a8bfc370003c92f2313ae' 
  AND token = 'l69GDSA5HNBvsLQUB3EVRZVM5Bm5afLXvcVfe7v6M0U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}