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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '191fa68ee1f6fb28b256b72576c3cd633b2b07e7b4c11574e8bcca2727a9c7e0' 
  AND token = 'nPa/KjRI6KEQUZFtE++4rsHlJixoTZ0qMihmBtui8iA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}