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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c741919e56fd17ac9a6b5d73ee0949f91ffce2c006f9fc1658d1f648c56fc2d3' 
  AND token = 'ZkC6V+dQPFpuC8JFaqYW/6/4hNiAALTQCofBaYHMx8g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}