SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '133c7928ad38f3a651403e9d82f754ad512f95b8d1c3bbacb709fba2a7e18bfa' 
  AND token = '+cu6rhfCwl6vCU2MpAYUPJ0ONB5FUAMYC4a+uiGVS5c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}