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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46abe8742b47466c074fa44f5b2c3f1e24b24301e343e3f074b2a6432fc50248' 
  AND token = 'XYdFUHtU9vgZCYi++498LyDH22rZAPPXhLW2hsOF7y4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}