SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dfc4c802931991c2b8e7d4518a2261947c5001a53b633287dbcdbbc2e118976f' 
  AND token = 'DCDeHAESAsG7oklk/2iW+Li7GiDTf9AcyKiK20ujg2Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}