SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '60bc4df8d166079acce346c1c4d5db0690e53de5414cc22a4f34212b3c45c024' 
  AND token = 'dDfJs2ejqHPvZuqJhSaiagHbQQUW22Snw/WwaLzRn2s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}