SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9bbf97e998cd949adcdc7e788d637dfd0e1b79e1f40ccb9eed2a72898f081924' 
  AND token = 'FWuVZkx/1JwLJjhqzdPi7vOh1QlfvUS5kcjUrmrwFaM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}