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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ab0665039ea8bca289b2b446a65ce4efd14ecee6f69e8d20a8d5b6e71e72a68' 
  AND token = 'kgToqz3/sKXrXaqyzMdtN+nyLru1HEvtz8+TKBaSzXg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}