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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80b523ac02d01ca3b1f6742691fd749ac9d5e319d7b82e39b42ab96bbb774f0f' 
  AND token = 'Z76xkR+fkSTYH3NdnXQNTMRby6lVriwP/tEb4GnUusw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}