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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b5aea685860cbe20f1eca5fd2a7ae0c9e29bdc86f7e8348061fa1e9424d10b7' 
  AND token = 'M9Queiy9pFS9BkWl7wlpyb2L4OBJfeY2ZHYuzSaAeGo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}