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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37f66db114f1c74649aedd2b1fbfed5311f6b369b2fcae1af4827183f14b3eaf' 
  AND token = '/Dz5RLcNGj6smL5YoYmlG7yjOIZc81y/0TUDhPaybXU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}